What appears to be the first case of a paraganglioma arising in the wall of the gallbladder is described. As there was no symptomatology of a catecholamine-secreting neoplasm, the tumor was believed to be nonfunctional. The chromaffin reaction was inconclusive since it was performed on tissue following prolonged formaldehyde solution fixation. The possible origins of this neoplasm occurring in such an unusual location are discussed.