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February 1973

A Kidney Transplant Patient With Fabry's Disease: Unusual Features

Author Affiliations

Rochester, Minn
From the Mayo Clinic and Mayo Foundation, Rochester, Minn.

Arch Surg. 1973;106(2):231-233. doi:10.1001/archsurg.1973.01350140087026

A patient with Fabry's disease underwent cadaveric renal transplantation. Unusual features of this case were as follows: (1) partial correction of the enzyme deficiency typical of the disease by the renal allograft; (2) the development of rapidly progressive pulmonary vascular obstruction and eventual fatal pulmonary embolism from subclavian vein thrombosis; and (3) surgical clipping of the inferior vena cava. This was done because of failure of and complications from anticoagulant therapy and did not in any way alter allograft function.