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February 1973

Coagulation Problems in Transplanted Organs.

Arch Surg. 1973;106(2):247-248. doi:10.1001/archsurg.1973.01350140103041

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This book consists of 12 scientific presentations with introductory and closing remarks by Dr. von Kaulla. These constitute the proceedings of an international symposium held in Munich, Germany, in 1970.

In the first presentation, Lechner and his associates from the University of Vienna, Austria, review their experience with orthotopic liver transplantations in 24 mongrel dogs. A characteristic pattern of altered coagulation factors occurred. During the anhepatic phase there was evidence of severe disseminated intravascular coagulation (DIC). If the transplanted liver was well preserved and if it functioned well, the clotting abnormalities subsequently regressed. However, if the liver did not function well, then local intravascular coagulation within the transplanted organ supervened. In subsequent presentations by Moraiu et al of the University of Lauvain, Belgium; by Bettigole and his associates from the Sloan-Kettering Institute, New York; and by Popov and his co-workers from Bonn University, Germany, similar data are presented, all of

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