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January 1974

125I-Fibrinogen Uptake and Bilateral Impedance RheographyDiagnosis of Postoperative Venous Thrombosis

Arch Surg. 1974;108(1):66-68. doi:10.1001/archsurg.1974.01350250056015

The detection of venous thrombosis by 125I-fibrinogen uptake and impedance rheography was compared in 80 randomly selected postoperative patients. The 125I-fibrinogen test was positive in ten (12.5%). Phlebography in nine of these patients showed thromboses in seven and possible thromboses in two. The impedance test was positive in three patients who also had abnormal results from the 125I-fibrinogen test. Phlebograms showed clots above the popliteal vein in these three. The 125I-fibrinogen method is better for studying the pathogenesis and prevention of thrombosis in a group of patients. The impedance method is better for studying patients with existing thombosis.