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April 1974

A Quarter Century With Splenectomy: Changing Concepts

Author Affiliations

Columbus, Ohio
From the departments of surgery (Drs. Fabri, Nick, and Zollinger) and medicine (Dr. Metz), Ohio State University, Columbus.

Arch Surg. 1974;108(4):569-575. doi:10.1001/archsurg.1974.01350280169028

Twenty-five years in surgery of the spleen is summarized in 1,944 patients who have been operated on for hypersplenism (48%), other splenic disease (9%), Hodgkin staging (4%), trauma (10%), and the increasing number with splenectomy incidental (29%) to gastrointestinal disease, hepatic disease, or transplantation. This experience focuses on changing trends in hematological indications including Hodgkin staging, leukemic reticuloendotheliosis, and myelofibrosis; current concepts in patient selection based on splenic sequestration; adjuncts to operative management, and the continuing challenge to prevent surgical complications and lower mortality.

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