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December 1974

Hypothermic Pulsatile Kidney Preservation: Comparative Analysis of Plasma Fractions

Author Affiliations

From the Department of Surgery, University of Minnesota, Minneapolis.

Arch Surg. 1974;109(6):816-818. doi:10.1001/archsurg.1974.01360060082022

Dog kidneys perfused with either cryoprecipitated plasma or silica gel fraction for 24 hours had normal function posttransplantation. In the absence of warm ischemia, albumin was as good a perfusate as cryoprecipitated plasma and silica gel fraction. If the kidneys were ischemically damaged, perfusion with albumin and plasma protein fraction (Plasmanate) did not prevent poor kidney function after transplantation. However, all ischemically damaged kidneys perfused with cryoprecipitated plasma or silica gel fraction functioned normally after transplantation. Because silica gel fraction can be stored easily; it is easier to use as a perfusate than cryoprecipitated plasma.