Four patients are reported with mycotic pseudotumors of the breast. Two of the granulomas were due to involvement by histoplasmosis, one by blastomycosis, and one by cryptococcosis. In the three patients who were treated surgically, tumor was suspected preoperatively in two and an infected cyst in one. The fourth granuloma, that due to cryptococcosis, was unsuspected clinically and discovered at autopsy. Surgical excision was effective therapy in those so treated. A critical review of the literature revealed only one other previously published case (cryptococcic mastitis) of deep mycosis of the breast.