Breast cancer screening, performed on asymptomatic women over 35 years of age, has identified 32 breast cancers in 30 of 4,500 women screened. Screening included a physical examination by trained technologists, thermography, and xeromammography. This represents 26% of the biopsies performed (116). Results of xeromammography were suspicious in 24 cases (80%), and results of physical examination were suspicious in 11 (37%). Only six were suspicious by both methods, with one other having changes that were considered benign. Fourteen (44%) were microinvasive or noninvasive. Only two (6%) had axillary metastases. Breast cancer detected by screening is in its "early" stages and is usually well localized. Operative management, including removal of the entire breast, has a significant potential for cure. Thirty patients with changes considered suspicious have not yet had biopsies. Improved overall survival depends on appropriate management of all patients screened.