This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
To the Editor.—In the March issue of the Archives, Dr Tilson et al are the authors of an article entitled "Compensatory Hypertrophy of the Ileum After Gastroduodenojejunal Exclusion" (Arch Surg 110:309, 1975). This is a study of the compensatory hypertrophy of the gut by examination of the ileum after bypass of pancreatobiliary secretions to the colon. Hypertrophy of the ileum occurred after esophagoileostomy and gastroduodenojejunal exclusion. A hypothesis seeking to reconcile the conflicting notions of intraluminal and hormonal stimuli was discussed by the authors.
In the discussion of the methods, there is a description of the experimental preparation. Animals were studied two weeks postoperatively. Absolutely no mention was made as to the nutritional support of the experimental animals. What kind of food was allowed? How much food was taken? Gut adaptation to luminal and hormonal factors depend, at least to some extent, on nutrient input. It was suprising to
YOUNG EA. Compensatory Hypertrophy of the Ileum. Arch Surg. 1975;110(8):1049. doi:10.1001/archsurg.1975.01360140193039
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: