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December 1976

Fat Overload With a 10% Soybean Oil Emulsion

Arch Surg. 1976;111(12):1391-1393. doi:10.1001/archsurg.1976.01360300081013

• A 10% soybean oil emulsion (Intralipid) has been demonstrated to be an effective means of delivering an adequate caloric intake via a peripheral vein. This emulsion has generally been considered safe and free of significant complications. This is a report of a child who initially thrived on this intravenously administered fat emulsion, then suddenly developed a life-threatening intolerance to the infusion, which appeared to be the "fat overload syndrome." This syndrome, seen frequently with earlier fat emulsions, has not been reported previously as a complication of the 10% soybean oil emulsion.

(Arch Surg 111:1391-1393, 1976)