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June 1977

Tumor Cells in Venous Blood Draining Mammary Carcinomas

Author Affiliations

From the Departments of Surgery (Dr Golinger) and Pathology (Drs Gregorio and Fisher), Shadyside Hospital and the University of Pittsburgh School of Medicine, Pittsburgh.

Arch Surg. 1977;112(6):707-708. doi:10.1001/archsurg.1977.01370060039005

• Tumor cells were identified in mammary vein blood in ten of 38 (26.6%) patients during total mastectomy with axillary dissection performed as the primary therapy for breast carcinoma (pathological stages I and II). This finding was analyzed with respect to 35 histological characteristics of the primary tumors. The presence of blood-borne tumor cells was inversely related to perineural space invasion, whereas there was no apparent relationship with the remaining 34 characteristics. The significance of blood-borne tumor cells remains unknown.

(Arch Surg 112:707-708, 1977)

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