[Skip to Navigation]
June 1978

Burn Unit Management of Toxic Epidermal Necrolysis

Author Affiliations

From the Burn Unit and the Departments of Surgery (Dr Demling and Ms Ellerbe) and Dermatology (Dr Lowe), University of Wisconsin Center for Health Sciences, Madison. Ms Ellerbe is now with Harborview Medical Center, Seattle.

Arch Surg. 1978;113(6):758-759. doi:10.1001/archsurg.1978.01370180100019

• Toxic epidermal necrolysis is the name given to a group of dermatologic disorders characterized by a separation of epidermis and dermis with a subsequent skin slough. The denuded areas have the appearance of a second-degree burn. The complications of infection, negative nitrogen balance, severe pain, and emotional instability are identical to those seen in the patient with major burns. There are difficulties in patient management and advantages in burn unit care. As with the major burn, care of the patient with skin loss from toxic epidermal necrolysis is extremely complex, requiring the expertise of a burn team along with that of the dermatologist.

(Arch Surg 113:758-759, 1978)