• Repair of secundum atrial septal defects in 75 patients older than age 40 years was associated with a good long-term result, from five to 21 years postoperatively, in 89% of patients who were class I and II preoperatively and in 86% of those in normal sinus rhythm preoperatively. Functional class III or IV, atrial fibrillation, a higher pulmonary artery mean pressure and higher pulmonary vascular resistance affected the prognosis adversely. Repair of atrial septal defect in adults did not reverse existing atrial fibrillation and did not protect against the onset of new atrial fibrillation.
(Arch Surg 113:1245-1247, 1978)
Magilligan DJ, Lam CR, Lewis JW, Davila JC. Late Results of Atrial Septal Defect Repair in Adults. Arch Surg. 1978;113(11):1245–1247. doi:10.1001/archsurg.1978.01370230035003