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January 1979

Postmortem Findings in Three Patients Treated With Intravenous Fat Emulsions

Arch Surg. 1979;114(1):66-68. doi:10.1001/archsurg.1979.01370250068014

• Three patients died of intercurrent illness in relation to intravenous nutrition with fat emulsions (20% Intralipid). In two cases, postmortem findings showed milky white, shiny, clotted lumps in the heart, with a fatty acid composition resembling that of fat emulsions. In vitro investigations make it likely that fibrin deposits in hyperlipemic plasma composed the lumps. In two cases, 30- to 50-μ Sudan-positive accumulations were found in the small vessels of the lungs, the cerebrum, and the kidneys.

(Arch Surg 114:66-68, 1979)