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March 1979

Management of Surgical Gastrointestinal Complications in Renal Transplant Recipients

Author Affiliations

From the Transplantation Service, Department of Surgery, University of Iowa College of Medicine, Iowa City. Dr Faro is now with the Department of Surgery, Creighton University School of Medicine.

Arch Surg. 1979;114(3):310-312. doi:10.1001/archsurg.1979.01370270080015

• Gastrointestinal (GI) complications developed in 19 (7.2%) of 265 patients after renal transplantation, and 3 (16%) patients died. Complications included colon perforations, colonic bleeding, small-bowel infarction, pancreatitis, subphrenic abscess, and upper GI tract bleeding. Ulcers located in the second portion of the duodenum developed in six patients; four of them required operation for massive hemorrhage, which occurred during or immediately after the administration of high-dose methylprednisolone for rejection. However, the association of methylprednisolone and colon perforation was not clear from this report. Early diagnosis and prompt operation for surgical-type GI complications in transplant recipients contribute to a low mortality.

(Arch Surg 114:310-312, 1979)