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October 1979

Desmoid Tumors and Mesenteric Fibromatosis in Gardner's Syndrome: Report of Kindred 109

Author Affiliations

From the Department of Pediatrics, State University of New York at Buffalo (Dr Naylor); the Department of Biology, Utah State University, Logan (Dr Gardner); and the Department of Surgery, University of Utah, Salt Lake City (Dr Richards).

Arch Surg. 1979;114(10):1181-1185. doi:10.1001/archsurg.1979.01370340087015

• Kindred 109, from which Gardner's syndrome was first described, now has 224 members, 28 of whom have inherited the syndrome. Among the group of 28, desmoid tumors or mesenteric fibromatosis or both have developed in eight (29%). In four patients, the fibrous dysplasia appeared to originate in postsurgical abdominal incisional scars; in two of these cases, the mesenteric involvement resulted in death. In one patient, the process was present in the mesentery at the original operation. In three patients, the fibrous dysplastic lesions were extraincisional, with no known trauma associated with their occurrence.

(Arch Surg 114:1181-1185, 1979)