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June 1980

Parietal Cell Vagotomy: Its Effect on Lower Esophageal Sphincter Function

Author Affiliations

From the Departments of Surgery (Drs Braasch and Sala), Thoracic and Cardiovascular Surgery (Dr Ellis), and Gastroenterology (Dr Crozier), Lahey Clinic Foundation, Boston.

Arch Surg. 1980;115(6):699-701. doi:10.1001/archsurg.1980.01380060007003

• Lower esophageal sphincter (LES) function was studied before and after parietal cell vagotomy in 11 patients with duodenal ulcer, none of whom experienced postoperative symptoms of gastroesophageal reflux. No changes were noted in any of the following variables measured: amplitude of LES pressure (before operation, 12.7 ± 1.18 mm Hg; after operation, 13.7 ± 0.73 mm Hg), length of LES (before, 3.85 ± 0.15 cm; after, 3.73 ± 0.17 cm), and adaptive response of LES (before, 1.26 ± 0.23; after, 1.31 ± 0.16). In man, LES possesses intrinsic tone, presumably related to tonic, myogenic activity independent of an extrinsic nerve supply.

(Arch Surg 115:699-701, 1980)