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November 1980

Experimental Skin Grafts and Transplantation Immunity

Arch Surg. 1980;115(11):1404. doi:10.1001/archsurg.1980.01380110136026

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The authors subtitle this book "A Recapitulation" and that it indeed is. This slim volume begins with an introduction that consists of a brief review of grafts, the immunologic response to them, and methods of delaying graft rejection. Then, a thorough and detailed review of the literature follows, dealing with the vascularization of skin grafts in autografts and first-set allografts, including stereomicroscopic, histochemical, and experimental data. Similar reviews of the literature dealing with second-set allografts and with xenograft rejection are then presented. Special topics are covered in separate chapters dealing with the effects of the size of grafts on allograft and xenograft rejection and with the behavior of preserved skin grafts.

The review of the literature presented in this book is detailed, thorough and objective, albeit not critical. It should be noted that the discussion of "transplantation immunity" is specifically directed at skin grafts and does not represent a general

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