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March 1983

Prognosis in Generalized Peritonitis: Relation to Cause and Risk Factors

Author Affiliations

From the Departments of Surgery (Drs Bohnen, Meakins, and McLean and Ms Boulanger) and Microbiology (Dr Meakins), Royal Victoria Hospital, McGill University, Montreal.

Arch Surg. 1983;118(3):285-290. doi:10.1001/archsurg.1983.01390030017003

• Generalized peritonitis was assessed in 176 patients, 67 (38%) of whom died. Cases were divided into causative groups: (1) appendicitis and perforated duodenal ulcer, (2) intraperitoneal origin other than appendix or duodenum, and (3) postoperative peritonitis. Mortalities were 10%, 50%, and 60%, respectively. Postoperative peritonitis was characterized by lack of influence of age on outcome, late operation, and more frequent organ failure. Delayed surgery carried a worse prognosis. Organ failure was a risk factor with 76% mortality, and was associated with late operation. Early surgery in organ failure improved survival. More sensitive indicators of early organ dysfunction might improve survival.

(Arch Surg 1983;118:285-290)

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