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April 1983

Surgical Therapy for Small-Bowel Carcinoid Tumors

Author Affiliations

From the Surgical Service, Ann Arbor Veterans Administration Medical Center (Drs Strodel and Eckhauser) and the Departments of Surgery, University of Michigan Medical Center, Ann Arbor (Drs Strodel, Eckhauser, and Thompson), and Henry Ford Hospital, Detroit (Dr Talpos).

Arch Surg. 1983;118(4):391-397. doi:10.1001/archsurg.1983.01390040003001

• Eighty-two symptomatic patients with carcinoid tumors of the small intestine were examined and treated over a 20-year period. Common clinical features included weight loss, diarrhea, and symptoms of intermittent bowel obstruction; 25 patients (30%) exhibited the carcinoid syndrome. Multiple carcinoid tumors occurred in 23 patients (28%), and hepatic metastases were present in 30 (37%). All patients underwent operation. The overall mortality was 7%, and the cumulative five-year survival rate was 59%. Two factors influenced prognosis after operation: hepatic metastases and incomplete resection. Other variables, including the sex and age of the patient and the size of the primary tumor, were of no additional prognostic value. Wide resection of the tumor, including regional lymph nodes, is indicated, regardless of the size of the primary tumor.

(Arch Surg 1983;118:391-397)