• Incomplete vagotomy is the most important cause of recurrent ulcer disease. Despite this, intraoperative vagotomy testing has not gained widespread acceptance. We used a technique with Congo red, a nontoxic azine dye that turns black (pH, 3.0) intraoperatively. The vagolytic effects of various general anesthetics has been shown. We found that halothane, used as a general anesthetic, combined with pentagastrin administration as a vagally synergistic stimulant, produced the most reliable, safe, and reproducible result when using Congo red intraoperatively.
(Arch Surg 1983;118:446-448)
Zucker K, Nelson C, Hoyt D, Saik RP. Impact of Choice of Anesthetic With Vagotomy Testing. Arch Surg. 1983;118(4):446–448. doi:10.1001/archsurg.1983.01390040056011