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August 1983

Carcinoma in Choledochal Cysts: Age-Related Incidence

Author Affiliations

From the Hepatobiliary Surgery Unit, Hammersmith Hospital, Royal Postgraduate Medical School, London. Dr Voyles is now with the Department of Surgery, University of Mississippi, Jackson.

Arch Surg. 1983;118(8):986-988. doi:10.1001/archsurg.1983.01390080088022

• We examined a case of malignant degeneration that occurred as a long-term complication of a choledochal cyst. Analysis of the literature shows the incidence of carcinoma varies with age at the initial appearance of symptoms. The child with a choledochal cyst that appears before 10 years of age carries a minimum risk (0.7%) of subsequent malignant degeneration compared with the patient in the second decade (6.8%) and older (14.3%). Data suggest that carcinoma may be readily overlooked at the time of choledochal cyst exploration. In light of the findings, an age-adjusted strategy for management should be used.

(Arch Surg 1983;118:986-988)