• We developed an experimental model of graded arterial stenosis to emulate conditions that might be encountered immediately following arterial grafting. Noninvasive measurements of systolic BP and limb blood flow were recorded with a Doppler probe and segmental air plethysmography, respectively, under conditions of different cardiac output and local arterial resistance. These measurements were correlated with direct intra-arterial pressure recordings and flow measurements taken with an electromagnetic flowmeter. There was an excellent correlation between noninvasive and intra-arterial measurements of systolic pressure over a range of cardiac outputs and degree of arterial stenosis. Pulse volume recordings correlated with direct measurements of blood flow at high and baseline cardiac outputs, but the calibration of pulse volume amplitude varied between cuff applications in this canine model. Noninvasive intraoperative monitoring techniques can faithfully represent known physiologic responses to graded arterial stenoses, irrespective of a high cardiac output or peripheral vasodilation.
(Arch Surg 1983;118:1152-1156)
Cambria RP, Walden R, Megerman J, L'Italien G, Abbott WM. Noninvasive Intraoperative Assessment of Arterial Reconstruction: Experimental Validation of the Role of Central and Regional Hemodynamics. Arch Surg. 1983;118(10):1152–1156. doi:10.1001/archsurg.1983.01390100026007
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: