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October 1984

Antibiotics and Infection

Arch Surg. 1984;119(10):1220. doi:10.1001/archsurg.1984.01390220092025

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The book is intended as a review of the principles and practice of antibiotic therapy in clinical infection. It begins with an outline of the pharmacokinetic principles of the drugs that include antimicrobial agents. The last chapter details the laboratory aspects of in vitro bacterial susceptibility testing. The remainder of the book contains a more practical discussion of antibiotic therapy and describes the properties, spectrum of activity, indications, use, and toxicity of different groups of antimicrobial, antiviral, antifungal and antiparasitic drugs. Only a few disappointing sentences are devoted to the so-called second and third generations of cephalosporins and the acylureide penicillins. The remaining chapters deal with the treatment of infections in specific sites such as the lungs or urinary tract, or infections due to specific microorganisms.

In the book's favor is its easy style. Facts and recommendations are presented in a clear and concise fashion. Controversies are avoided where possible.

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