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July 1986

Hepatocellular Carcinoma Presenting With Intractable Diarrhea: A Radiologic-Pathologic Correlation

Author Affiliations

From the Departments of Diagnostic Radiology (Drs Steiner, Velt, and Gutierrez) and Surgery (Dr Schwartz), University of Rochester School of Medicine and Dentistry; and the Department of Medicine, Genesee Hospital (Dr Chey), Rochester, NY.

Arch Surg. 1986;121(7):849-851. doi:10.1001/archsurg.1986.01400070119025

• A 44-year-old woman with hepatocellular carcinoma presented with intractable watery diarrhea and her condition was evaluated angiographically. Surgical ablation of the tumor resulted in complete resolution of the diarrhea. The tumor cells of the hepatocellular carcinoma were found to contain vasoactive intestinal polypeptide, gastrin, and prostaglandinlike immunoactivity. To our knowledge, this is the first report of such an association.

(Arch Surg 1986;121:849-851)