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August 1986

Multiple Granular Cell Tumors: A Familial Occurrence in Children

Author Affiliations

From the Departments of Surgery (Dr Rifkin) and Pathology (Dr Palmer), The Jewish Hospital of St Louis, and the Division of Pediatric Surgery, St Louis Children's Hospital and Washington University School of Medicine, St Louis (Drs Blocker and Ternberg).

Arch Surg. 1986;121(8):945-947. doi:10.1001/archsurg.1986.01400080091017

• A 23-year-old black woman and her 6-year-old son, both with multiple granular cell tumors, are described herein. The mother and son both presented as children with multiple granular cell tumors. This is the first reported case of multiple lesions arising in childhood in successive generations. Only two other case studies of familial granular cell tumors have been reported, but in neither of these cases did multiple tumors present initially in both family members during childhood. A preponderance of multicentric lesions is reported in blacks. The tumors recurred locally in some of the sites where there were inadequate surgical margins, emphasizing the need for complete excision.

(Arch Surg 1986;121:945-947)

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