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November 1986

Ovarian Carcinoma: The Significance of Restaging Laparotomies With Negative Outcomes

Author Affiliations

From the Lombardi Cancer Center, Division of Gynecologic Oncology, Georgetown University School of Medicine, Washington, DC.

Arch Surg. 1986;121(11):1262-1264. doi:10.1001/archsurg.1986.01400110048008

• The role of restaging laparotomy in the treatment of ovarian carcinoma is currently being reevaluated. This study was initiated to examine the predictive value of a negative outcome. Between November 1974 and October 1983, sixtythree patients with no clinical evidence of disease underwent 70 restaging laparotomies for ovarian carcinoma. The findings of 34 (49%) of these procedures were negative for residual disease. Patient follow-up ranged from 30 to 137 months. Twenty-eight patients are alive with no evidence of disease with a median follow-up of 62 months. Four patients have died of a second primary tumor. Only two patients had recurrence of their ovarian carcinoma following restaging laparotomy with negative findings (recurrence rate, 5.9%; 13.3% for patients with advanced disease). Patients with negative findings at restaging laparotomy have an excellent prognosis and a good chance of being cured of their disease.

(Arch Surg 1986;121:1262-1264)

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