• During the 11-year period from 1977 through 1987, hepatic resections were carried out in 120 patients with hepatocellular carcinoma (HCC). Twenty-five had HCCs smaller than 5 cm in diameter. There were 97 male and 23 female patients, with an average age of 51.5 years. Among them, 45.8% had liver cirrhosis and 80.8% were positive for hepatitis B surface antigen. Fourteen with ruptured HCCs underwent hepatic resection to control the intra-abdominal hemorrhage. Operative mortality within one month after surgery was 4.1%. The postoperative course was complicated by pleural effusion in 5.8%, subphrenic abscess in 2.5%, postoperative bleeding in 1.6%, hepatic failure in 1.6%, and bile leakage in 0.8% of the patients. The overall five-year survival rate in this series was 25.9%, while survival for the last five years was better (42.3% vs 11.9% for patients treated between 1977 and 1982). The cumulative survival rate had no relation to tumor rupture or liver cirrhosis. The group of patients with smaller tumors (diameter, < 5 cm) or without vascular invasion by tumor had better survival.
(Arch Surg 1989;124:1025-1028)
Chen M, Hwang T, Jeng LB, Jan Y, Wang C, Chou F. Hepatic Resection in 120 Patients With Hepatocellular Carcinoma. Arch Surg. 1989;124(9):1025–1028. doi:10.1001/archsurg.1989.01410090031006
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.