• The efficacy of stereotaxic aspiration biopsy was evaluated in 300 consecutive patients with nonpalpable mammographic lesions. Sixty-eight patients (23%) had suspicious or malignant aspirates; all cases were proved malignant by subsequent examination of operative specimens. Two hundred sixteen patients (72%) had benign aspirates. Of these, 65 were confirmed by operation and 151 had subsequent mammography at 6- and 12-month intervals with no demonstrable mammographic change. In 10 instances (3%), the aspirates were atypical, and in six (2%), nondiagnostic. Biopsy specimens were obtained in all 16 instances, and eight were malignant. The sensitivity of stereotaxic breast aspiration for the diagnosis of cancer was 96%, and the specificity was 100%. Our experience confirms the efficacy of stereotaxic aspiration for the initial evaluation of mammographically detected, nonpalpable lesions.
(Arch Surg. 1991;126:1137-1140)
Mitnick JS, Vazquez MF, Roses DF, Harris MN, Gianutsos R, Waisman J. Stereotaxic Localization for Fine-Needle Aspiration Breast Biopsy: Initial Experience With 300 Patients. Arch Surg. 1991;126(9):1137–1140. doi:10.1001/archsurg.1991.01410330099014
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