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July 1992

Limb Perfusion: An Objective Measure of Hemodynamic Improvement After Angioplasty

Arch Surg. 1992;127(7):806-811. doi:10.1001/archsurg.1992.01420070066013

• Forty-four patients undergoing femoropopliteal angioplasty were studied by magnetic resonance blood flowmetry to determine quantitative limb perfusion. Baseline limb perfusion averaged 0.52±0.15 mL/min per 100 cc of tissue. Perfusion values for successful angioplasties rose within 72 hours to a mean of 1.40±0.31 mL/min per 100 cc of tissue. There were five early failures (<30 days), in which perfusion fell to 0.54±0.10 mL/min per 100 cc of tissue; at 6 months, 12 additional angioplasties had failed, with limb perfusion values of 0.68±0.16 mL/min per 100 cc of tissue. At 6 months, perfusion in four additional limbs had decreased to between 0.7 and 1.0 mL/min per 100 cc of tissue, with a mean change of 0.59 mL/min per 100 cc of tissue; duplex ultrasound imaging at these sites showed restenoses ranging from 50% to 75%. We conclude that lower-leg limb perfusion appears to be a reliable measure of hemodynamic improvement after femoropopliteal angioplasty and may provide an early indicator of impending failure.

(Arch Surg. 1992;127:806-811)