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November 1992

Extended Indications for Functional Limb-Sparing Surgery in Extremity Sarcoma Using Complex Reconstruction

Author Affiliations

From the Departments of General Oncologic Surgery (Drs Paz, Wagman, Terz, and Moscarello), Plastic and Reconstructive Surgery (Drs Chandrasekhar and Lorant), and Biostatistics (Dr Odom-Maryon), City of Hope National Medical Center, Duarte, Calif.

Arch Surg. 1992;127(11):1278-1281. doi:10.1001/archsurg.1992.01420110020005

• From 1980 to 1991, 29 patients underwent complex reconstruction following extremity sarcoma resection. Soft tissue was the site of origin in 15 patients (52%) and bone was the site of origin in 14 patients (48%), with 20 sarcomas (69%) in the lower extremity. Resection consisted of the following procedures: extended anatomical soft-tissue resections (21 patients [72%]), bone resections (18 patients [62%]), and joint resections (14 patients [48%]). Reconstruction involved the following: myocutaneous flaps (20 patients [69%]), joint prosthesis (eight patients [28%]), and bone reconstruction (15 patients [52%]). There was no surgical mortality; one patient required an amputation owing to surgical complications. The site of the first failure was local (four [31 %] of 13 patients), lung (five patients [38%]), others (four patients [31 %]). At a median follow-up of 23 months, 18 patients (62%) had no evidence of disease, 27 (93%) had no local disease, 21 (72%) had good extremity function, three (10%) had major disabilities, and five (17%) underwent amputations. Local control improved when the margin of resection was larger than 10 mm. Disease-free survival was 67% at 3 years. Overall survival was 51% at 5 years. Tumor size was an independent predictor of overall survival. Local recurrence did not affect overall survival.

(Arch Surg. 1992;127:1278-1281)

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