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May 1995

Surgical Treatment of Recurrent Pyogenic Cholangitis

Author Affiliations

From the Departments of Surgery (Drs Stain, Incarbone, Guthrie, Rivera-Lara, Parekh, and Yellin) and Radiology (Dr Ralls), University of Southern California School of Medicine, Los Angeles.

Arch Surg. 1995;130(5):527-533. doi:10.1001/archsurg.1995.01430050077013

Objective:  To examine the evolving operative strategies in the treatment of recurrent pyogenic cholangitis (RPC).

Design:  Case series of patients with RPC treated surgically at the Los Angeles County-University of Southern California Medical Center between 1980 and 1994.

Setting:  Public teaching hospital.

Patients:  Twenty patients with RPC were studied. The clinical diagnosis of RPC was made in patients with a syndrome of chronic intermittent attacks of biliary sepsis associated with intrahepatic biliary strictures and intrahepatic stones.

Main Outcome Measure:  The need for repeated biliary intervention after surgical treatment of RPC.

Results:  Four patients had a hepatic lobectomy without biliary enteric bypass. One patient had an uneventful course. Three patients had postoperative biliary sepsis, and one of these patients died. A hepaticojejunostomy without a cutaneous stoma was performed in eight patients. Five (63%) of these eight required repeated operation for biliary sepsis 1 to 4 years after surgery. In eight patients, a Rouxen-Y hepaticojejunostomy was performed after attempted clearance of intrahepatic stones with construction of a temporary cutaneous stoma. Postoperatively, these eight patients had 16 transstomal endoscopic cholangiograms (mean follow-up, 10 months). Stones proximal to intrahepatic strictures were identified in seven endoscopic sessions in five of these patients (63%). The stones were removed, and the strictures were endoscopically dilated. None required repeated biliary operation.

Conclusion:  RPC is a progressive, lifelong disease. Construction of a hepaticojejunostomy with a cutaneous stoma allows future therapeutic intervention without the need for repeated surgery.(Arch Surg. 1995;130:527-533)

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