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Riou and his coauthors have made some intriguing and clinically useful observations relating to the occurrence of second primary cancers before or after the diagnosis and treatment of cutaneous malignant melanoma. The fact that the incidence of malignant melanoma has been increasing faster than any other cancer in the United States makes such observations particularly pertinent. In this regard, prior melanoma is considered a possible risk factor for screening programs, and it is surprising, therefore, that no second primary melanomas were noted in this series. Possibly this was owing to the relatively short mean follow-up times. Another intriguing observation in this study is the fact that mycosis fungoides represented 58% of the 12 lymphoma lesions that were identified! This rare form of cutaneous lymphoma represents a very small percentage of all lymphomas in our overall population and among the posttransplant lymphomas that have been reported.
The authors address the potential
Lawrence W. Invited Commentary. Arch Surg. 1995;130(10):1061. doi:10.1001/archsurg.1995.01430100039008
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