Efficacy of Homeopathic Arnica: A Systematic Review of Placebo-Controlled Clinical Trials | Complementary and Alternative Medicine | JAMA Surgery | JAMA Network
[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
Ernst  EKaptchuk  TJ Homeopathy revisited.  Arch Intern Med. 1996;1562162- 2164Google ScholarCrossref
Ernst  EedHahn  Eed Homeopathy: A Critical Appraisal.  Oxford, England Butterworth-Heinemann Publishers1998;
Ernst  E The heresy of homeopathy.  Br Homeopathic J. 1998;8728- 32Google ScholarCrossref
Kleijnen  JKnipschild  PTer Riet  G Clinical trials of homeopathy.  BMJ. 1991;302316- 332Google ScholarCrossref
Linde  KClausius  NRamirez  G  et al.  Are the clinical effects of homeopathy placebo effects? a meta-analysis of placebo-controlled trials.  Lancet. 1997;350834- 843Google ScholarCrossref
Vandenbrouk  JP Homeopathy trials, going nowhere.  Lancet. 1997;350824Google ScholarCrossref
Langman  MJS Homeopathy trials: reasons for good ones, but are they warranted?  Lancet. 1997;350825Google ScholarCrossref
Barnes  JResch  KLErnst  E Homeopathy for postoperative ileus: a meta-analysis.  J Clin Gastroenterol. 1997;25628- 633Google ScholarCrossref
Ernst  EBarnes  J Are homoeopathic remedies effective for delayed-onset muscle soreness? a systematic review of placebo-controlled trials.  Perfusion. 1998;114- 8Google Scholar
Boissel  JPErnst  EFisher  PFülgraff  GGaratini  Sde Klerk  E Overview of data from homeopathic medicine trials.  European Reports Brussels, Belgium EU Rep1996;Google Scholar
Hofmeyer  GJ Postpartum homeopathic Arnica montana: a potency-finding pilot study.  Br J Clin Pract. 1990;44619- 621Google Scholar
Lökken  PStraumsheim  PATveiten  DSkjelbred  PBorchgrevink  CF Effects of homeopathy on pain and other events after acute trauma.  BMJ. 1995;3101439- 1442Google ScholarCrossref
Bendre  VVDharmudhikari  SD Arnica montana and hypericum in dental practice.  Hahnemannian Gleanings. 1980;4770- 72Google Scholar
Jadad  ARMoore  RACarrol  D  et al.  Assessing the quality of reports of randomized clinical trials: is blinding necessary?  Control Clin Trials. 1996;171- 12Google ScholarCrossref
Hildebrandt  GEltze  C Über die Wirksamkeit verschiedener Potenzen von Arnica beim experimentell erzeugten Muskelkater.  Erfahrungsheilkunde. 1984;7430- 435Google Scholar
Kaziro  GSN Metronidazole (Flagyl) and Arnica montana in the prevention of postsurgical complications: a comparative placebo controlled clinical trial.  Br J Oral Maxillofac Surg. 1984;2242- 49Google ScholarCrossref
Pinsent  RJFMBaker  GPIIves  GDavey  RWJonas  S Does arnica reduce pain and bleeding after dental extraction?  Midland Homeopathy Res Group Newslett. 1984;1171- 72Google Scholar
Tveiten  DBruseth  SBorchgrevink  CFLøhne  K Effect of arnica D30 on hard physical exercise: a double-blind controlled trial during the Oslo Marathon.  Tidsskr Nor Loegeforen. 1991;1113630- 3631Google Scholar
Gibson  JHaslam  YLaurneson  LNewman  PPitt  RRobins  M Double-blind trial of arnica in acute trauma patients.  Homeopathy. 1991;4154- 55Google Scholar
Campbell  A Two pilot controlled trials of Arnica montana Br Homeopathic J. 1976;65154- 158Google ScholarCrossref
Savage  RHRoe  PF A further double blind trial to assess the benefit of Arnica montana in acute stroke illness.  Br Homoeopathic J. 1978;67211- 222Google ScholarCrossref
Livingston  R Homeopathy, Evergreen Medicine.  Poole, England Asher Press1991;
Kayne  SB Homeopathic Pharmacy.  Edinburgh, Scotland Churchill-Livingstone1997;
Special Article
November 1998

Efficacy of Homeopathic Arnica: A Systematic Review of Placebo-Controlled Clinical Trials

Author Affiliations

From the Department of Complementary Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, Exeter, England.

Arch Surg. 1998;133(11):1187-1190. doi:10.1001/archsurg.133.11.1187

Background  The efficacy of homeopathic remedies has remained controversial. The homeopathic remedy most frequently studied in placebo-controlled clinical trials is Arnica montana.

Objective  To systematically review the clinical efficacy of homeopathic arnica.

Materials and Methods  Computerized literature searches were performed to retrieve all placebo-controlled studies on the subject. The following databases were searched: MEDLINE, EMBASE, CISCOM, and the Cochrane Library. Data were extracted in a predefined, standardized fashion independently by both authors. There were no restrictions on the language of publications.

Results  Eight trials fulfilled all inclusion criteria. Most related to conditions associated with tissue trauma. Most of these studies were burdened with severe methodological flaws. On balance, they do not suggest that homeopathic arnica is more efficacious than placebo.

Conclusion  The claim that homeopathic arnica is efficacious beyond a placebo effect is not supported by rigorous clinical trials.