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Article
December 1929

EMBOLISM IN BRONCHOGENIC INFECTION OF THE LUNG

Author Affiliations

NEW HAVEN, CONN.; CHICAGO
From the Department of Surgery, University of Chicago.

Arch Surg. 1929;19(6):1279-1291. doi:10.1001/archsurg.1929.01150060341020
Abstract

In another publication1 are described the effects on the lung of dogs produced by embolic and intrabronchial inoculation, employed separately and combined. It appeared that interaction of both of these portals of entry for organisms to the lung pertains to the pathogenesis of certain postoperative abscesses of the lung in man of obscure origin.

These experiments, moreover, emphasized the fact that abscess develops readily from embolic inoculation of the parenchyma of the lung, but with great difficulty, if at all, after intrabronchial implantation of the same infecting agents, although used in enormously larger quantity. This phenomenon is considered further in the present communication.

Others have called attention to the same circumstance. One explanation has been that embolism interferes with the blood supply of the part inoculated and lowers its resistance.2 Another reason, more generally given,3 is that material deposited in the tracheobronchial tract is quickly removed by

References
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Van Allen, C. M.; Adams, W. E., and Hrdina, L. S.: Bronchogenic Contamination in Embolic Abscess of the Lung, p. 1262 of this issue.
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