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December 1969

Phase-Shift Balloon Pumping in Medically Refractory Cardiogenic Shock: Results in 27 Patients

Author Affiliations

Brooklyn, NY
From the Departments of Surgery, State University of New York Downstate Medical Center and Maimonides Medical Center, Brooklyn, NY.

Arch Surg. 1969;99(6):739-743. doi:10.1001/archsurg.1969.01340180063013

Pump failure is considered to be the primary pathophysiologic defect in cardiogenic shock secondary to acute myocardial infarction. Several investigators have reported mortality in 85% to 95% of patients with this syndrome.1-4 In those with cardiogenic shock accompanied by pulmonary edema, the fatality rate was 100% in a series of 241 patients with acute myocardial infarction studied by E. Greif, according to an oral communication with him on Oct 28, 1968. Available pharmacologic therapies which augment myocardial contractility or raise systemic blood pressure also increase the internal work of the heart and, therewith, its oxygen demand. Use of these agents does not appear to be associated with an increased survival rate.

Since June 1967 a mechanical means of circulatory support for patients in refractory cardiogenic shock, the intraaortic phase-shift balloon pump, has been under clinical trial. Our experimental laboratory studies and initial clinical evaluation indicated that balloon pumping effectively

Griffith, G.C., et al:  The Treatment of Shock Associated With Myocardial Infarction ,  Circulation 9:527-532 ( (April) ) 1954.Crossref
Friedberg, C.:  Cardiogenic Shock in Acute Myocardial Infarction ,  Circulation 23:325-330 ( (March) ) 1961.Crossref
Johnson, J.B., and Cross, E.B.:  Hearts Too Good to Die: Problems in Acute Myocardial Infarction ,  J Nat Med Assoc 59:1-6 ( (Jan) ) 1967.
Cronin, R.F.P.; Moore, S.; and Marpole, D.G.:  Shock Following Myocardial Infarction: A Clinical Survey of 140 Cases ,  Canad Med Assoc J 93:57-63 ( (July) ) 1965.
Schilt, W., et al:  Temporary Nonsurgical Intraarterial Cardiac Assistance ,  Trans Amer Soc Artif Intern Organs 13:322-327, 1967.
Kantrowitz, A., et al:  Initial Clinical Experience With Intraaortic Balloon Pumping in Cardiogenic Shock ,  JAMA 203:113-118 ( (Jan) ) 1968.Crossref
Kantrowitz, A., et al:  Clinical Experience With Cardiac Assistance by Means of Intraaortic Phase-shift Balloon Pumping ,  Trans Amer Soc Artif Intern Organs 14:344-348, 1968.
Yahr, W.Z., et al:  Cardiogenic Shock: Dynamics of Coronary Blood Flow With Intra-Aortic Phase-shift Balloon Pumping ,  Surg Forum 19:142-144, 1968.
Kantrowitz, A., et al:  Technique of Femoral Artery Cannulation For Phase-shift Balloon Pumping ,  J Thorac Cardiovasc Surg 56:219-220 ( (Aug) ) 1968.