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In this excellent book, Dr Lynch and his contributors have brought together clearly and concisely an enormous amount of data that should be of value to every physician. The reader will find well-written chapters on basic genetics, immunology, oncogenic viruses, cytogenetics, nongenetic factors in causing neoplasia, and cancers of specific sites such as breast, colon, lung, skin, and the nervous system. There is also sound advice on genetic counseling, stressing the limitations of our knowledge.
Admittedly, the field of cancer genetics is just coming into being, but its importance and potential benefits have received less attention than deserved. Patients at a high risk from cancer (and any other disease) should be identified, informed, and followed up, hopefully to prevent catastrophe.
This book will greatly aid the physician to fulfill that responsibility which goes beyond the ancient injunction of "primum nocere."
GOLDWYN RM. Cancer Genetics. Arch Surg. 1976;111(6):726. doi:10.1001/archsurg.1976.01360240106028
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