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Article
August 1976

Subcutaneous Nodules as a Manifestation of Onchocerciasis: A Rare Condition in the United States

Author Affiliations

From the departments of surgery (Drs Palomar and Grannis) and pathology (Dr Bray), Public Health Service Hospital, and the Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine (Dr Beaver), New Orleans.

Arch Surg. 1976;111(8):909-911. doi:10.1001/archsurg.1976.01360260077020
Abstract

• Although infection with tissue nematodes is a significant health problem in many parts of the world, such cases are unusual in the continental United States. This report describes a case of Onchocerca volvulus infection, acquired by a 38-year-old female missionary in northern Brazil, that manifested as subcutaneous nodules in the groin and flank two years after the patient's return to the United States. A year previously, a wrong diagnosis of Wuchereria bancrofti was made at biopsy. At that time, treatment with diethylcarbamazine citrate had to be discontinued because of intense pruritus. Examination of a wet saline impression smear of a new biopsy specimen showed the adult worms to have regularly arranged outer annular ridges, which, together with the pruritus after treatment with diethylcarbamazine (a positive Mazzotti test), led to the diagnosis of onchocerciasis. Retreatment with diethylcarbamazine again caused pruritus, but this was tolerated as were subsequent treatments.

(Arch Surg 111:909-911, 1976)

References
1.
 Expert Committee on Onchocerciasis: Second Report ,  WHO Tech Rep Ser 335:6-9, 1966.
2.
Assis-Masri G, Little MD:  A case of ocular onchocerciasis in Colombia .  Trans R Soc Trop Med Hyg 59:717, 1965.Crossref
3.
Little MD, D'Alessandro A:  Onchocerciasis in Colombia. Parasitologic findings in the first observed focus .  Am J Trop Med Hyg 19:831-836, 1970.
4.
Moraes MAP, Chaves GM:  Onchocerciasis in Brazil: New findings among the Yanomama Indians .  Bull Pan Am Health Org 8:95-99, 1974.
5.
Beaver PC, Horner GS, Bilos JZ:  Zoonotic onchocerciasis in a resident of Illinois and observations on the identification of Onchocerca species .  Am J Trop Med Hyg 23:4, 595-607, 1974.
6.
Neafie RC:  Morphology of Onchocerca volvulus .  Am J Clin Pathol 57:574-586, 1972.
7.
Buck AA (ed):  Onchocerciasis: Symptomatology. Pathology, Diagnosis . Geneva, World Health Organization, 1974.
8.
Beaver PC, Orihel TC:  Human infection with filariae of animals in the United States .  Am J Trop Med Hyg 14:1010-1029, 1965.
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