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  • Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial

    Abstract Full Text
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    JAMA. 2019; 322(13):1261-1270. doi: 10.1001/jama.2019.11825

    This randomized clinical trial compares the effects of high-dose vitamin C vs placebo on the incidence of organ failure and biomarkers of inflammation and vascular injury in patients in the intensive care unit (ICU) with sepsis and ARDS.