JAMA
Original Investigation
July 28, 2020
Rowan T . Chlebowski , MD, PhD; Garnet L. Anderson, PhD; Aaron K. Aragaki, MS; JoAnn E. Manson, MD, DrPH; Marcia L. Stefanick, PhD; Kathy Pan, MD; Wendy Barrington, PhD; Lewis H. Kuller, MD; Michael S. Simon, MD; Dorothy Lane, MD; Karen C. Johnson, MD; Thomas E. Rohan, MBBS; Margery L. S. Gass, MD; Jane A. Cauley, PhD; Electra D. Paskett, PhD; Maryam Sattari, MD; Ross L. Prentice, PhD
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JAMA. 2020; 324(4):369-380. doi: 10.1001/jama.2020.9482This study reports 20-year breast cancer incidence among participants in Women’s Health Initiative (WHI) trials randomized to conjugated equine estrogen (CEE) alone or with medroxyprogesterone acetate vs placebo.
JAMA Network Open
Original Investigation
Oncology
June 30, 2020
Veronica L. Irvin, PhD, MPH; Zhenzhen Zhang, PhD, MPH; Michael S. Simon, MD; Rowan T . Chlebowski , MD, PhD; Shiuh-Wen Luoh, MD, PhD; Aladdin H. Shadyab, PhD; Jessica L. Krok-Schoen, PhD; Fred K. Tabung, PhD; Lihong Qi, PhD; Marcia L. Stefanick, PhD; Pepper Schedin, PhD; Sonali Jindal, MD
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JAMA Netw Open. 2020; 3(6):e207227. doi: 10.1001/jamanetworkopen.2020.7227This cohort study uses data from the Women’s Health Initiative study to compare the prognostic features and mortality rate of women with interval breast cancers diagnosed within 1 year or between 1 and 2.5 years of a mammogram with negative results with the prognostic features and mortality rate of women with breast cancers detected by screening.
JAMA Network Open
Original Investigation
Nutrition, Obesity, and Exercise
July 24, 2019
Yangbo Sun, MD, PhD; Buyun Liu, MD, PhD; Linda G. Snetselaar, PhD; Robert B. Wallace, MD; Bette J. Caan, DrPH; Thomas E. Rohan, MBBS, PhD, DHSc; Marian L. Neuhouser, PhD; Aladdin H. Shadyab, PhD; Rowan T . Chlebowski , MD, PhD; JoAnn E. Manson, MD, DrPH; Wei Bao, MD, PhD
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JAMA Netw Open. 2019; 2(7):e197337. doi: 10.1001/jamanetworkopen.2019.7337This cohort study uses data from women enrolled in the Women’s Health Initiative (WHI) to examine the associations of normal-weight central obesity with all-cause and cause-specific mortality among postmenopausal women in the United States.
JAMA Oncology
Original Investigation
February 1, 2019
Neil M. Iyengar, MD; Rhonda Arthur, PhD; JoAnn E. Manson, MD, DrPH; Rowan T . Chlebowski , MD, PhD; Candyce H. Kroenke, ScD; Lindsay Peterson, MD; Ting-Yuan D. Cheng, PhD; Elizabeth C. Feliciano, ScD; Dorothy Lane, MD; Juhua Luo, PhD; Rami Nassir, PhD; Kathy Pan, MD; Sylvia Wassertheil-Smoller, PhD; Victor Kamensky, MS; Thomas E. Rohan, MBBS, PhD, DHSc; Andrew J. Dannenberg, MD
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JAMA Oncol. 2019; 5(2):155-163. doi: 10.1001/jamaoncol.2018.5327This secondary analysis of the Women’s Health Initiative randomized clinical trial and observational study cohort investigates the association between body fat and breast cancer risk in postmenopausal women with normal body mass index.
JAMA Ophthalmology
Comment & Response
November 1, 2018
Victoria L. Tseng, MD, PhD; Rowan T . Chlebowski , MD, PhD; Fei Yu, PhD; Jane A. Cauley, DrPH; Wenjun Li, PhD; Fridtjof Thomas, PhD; Beth A. Virnig, PhD; Anne L. Coleman, MD, PhD
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JAMA Ophthalmol. 2018; 136(11):1313-1314. doi: 10.1001/jamaophthalmol.2018.3347Notice of Retraction and Replacement. Tseng et al. Association of cataract surgery with mortality in older women: findings from the Women’s Health Initiative. JAMA Ophthalmol. 2018;136(1):3-10
JAMA Oncology
Original Investigation
October 11, 2018
Rowan T . Chlebowski , MD, PhD; Aaron K. Aragaki, MS; Garnet L. Anderson, PhD; Michael S. Simon, MD, MPH; JoAnn E. Manson, MD, DrPH; Marian L. Neuhouser, PhD; Kathy Pan, MD; Marcia L. Stefanick, PhD; Thomas E. Rohan, MBBS, PhD; Dorothy Lane, PhD; Lihong Qi, PhD; Linda Snetselaar, PhD; Ross L. Prentice, PhD
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JAMA Oncol. 2018; 4(10):e181212. doi: 10.1001/jamaoncol.2018.1212This secondary analysis of the Women’s Health Initiative randomized clinical trial investigates the association of a low-fat dietary pattern vs a usual diet comparison with overall survival among women with breast cancer.
JAMA Ophthalmology
Original Investigation
January 1, 2018
Victoria L. Tseng, MD, PhD; Rowan T . Chlebowski , MD, PhD; Fei Yu, PhD; Jane A. Cauley, DrPH; Wenjun Li, PhD; Fridtjof Thomas, PhD; Beth A. Virnig, PhD; Anne L. Coleman, MD, PhD
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JAMA Ophthalmol. 2018; 136(1):3-10. doi: 10.1001/jamaophthalmol.2017.4512This cohort study examines the association between cataract surgery and total and cause-specific mortality in older patients with cataract in the Women’s Health Initiative.
JAMA
Original Investigation
September 12, 2017
JoAnn E. Manson, MD, DrPH; Aaron K. Aragaki, MS; Jacques E. Rossouw, MD; Garnet L. Anderson, PhD; Ross L. Prentice, PhD; Andrea Z. LaCroix, PhD; Rowan T . Chlebowski , MD, PhD; Barbara V. Howard, PhD; Cynthia A. Thomson, PhD; Karen L. Margolis, MD, MPH; Cora E. Lewis, MD, MSPH; Marcia L. Stefanick, PhD; Rebecca D. Jackson, MD; Karen C. Johnson, MD, MPH; Lisa W. Martin, MD; Sally A. Shumaker, PhD; Mark A. Espeland, PhD; Jean Wactawski-Wende, PhD; for the WHI Investigators
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JAMA. 2017; 318(10):927-938. doi: 10.1001/jama.2017.11217This observational follow-up (cumulative 18 years) of postmenopausal women enrolled in 2 RCTs compared rates of all-cause, cardiovascular, and cancer mortality between groups receiving hormone therapy (conjugated equine estrogens [CEE] plus medroxyprogesterone acetate) or CEE alone vs placebo.
JAMA Oncology
Original Investigation
December 1, 2016
Reina Haque, PhD; Jiaxiao Shi, PhD; Joanne E. Schottinger, MD; Joanie Chung, MPH; Chantal Avila, MA; Britta Amundsen, MA; Xiaoqing Xu, PharmD; Ana Barac, MD; Rowan T . Chlebowski , MD
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JAMA Oncol. 2016; 2(12):1590-1597. doi: 10.1001/jamaoncol.2016.0429This cohort study compares the risk of cardiovascular disease in breast cancer survivors who received tamoxifen, aromatase inhibitors, both, or neither during a long-term follow-up period.
JAMA Oncology
Comment & Response
November 1, 2015
Marian L. Neuhouser, PhD, RD; Rowan T . Chlebowski , MD, PhD; Garnet L. Anderson, PhD
JAMA Oncol. 2015; 1(8):1171-1171. doi: 10.1001/jamaoncol.2015.3313
JAMA Oncology
Original Investigation
June 1, 2015
Rowan T . Chlebowski , MD, PhD; Thomas E. Rohan, PhD; JoAnn E. Manson, MD, DrPH; Aaron K. Aragaki, MS; Andrew Kaunitz, MD; Marcia L. Stefanick, PhD; Michael S. Simon, MD; Karen C. Johnson, MD, MPH; Jean Wactawski-Wende, PhD; Mary J. O’Sullivan, MD; Lucile L. Adams-Campbell, PhD; Rami Nassir, PhD; Lawrence S. Lessin, MD; Ross L. Prentice, PhD
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JAMA Oncol. 2015; 1(3):296-305. doi: 10.1001/jamaoncol.2015.0494This study examined the influences of hormone therapy on breast cancer incidence during early and late postintervention phases in the Women’s Health Initiative trials, finding greater adverse influence for estrogen + progestin use and somewhat greater benefit for use of estrogen alone.
JAMA
Comment & Response
January 22, 2014
JoAnn E. Manson, MD, DrPH; Rowan T . Chlebowski , MD, PhD; Aaron K. Aragaki, MS
JAMA. 2014; 311(4):417-418. doi: 10.1001/jama.2013.285163
JAMA
Original Investigation
October 2, 2013
JoAnn E. Manson, MD, DrPH; Rowan T . Chlebowski , MD, PhD; Marcia L. Stefanick, PhD; Aaron K. Aragaki, MS; Jacques E. Rossouw, MD; Ross L. Prentice, PhD; Garnet Anderson, PhD; Barbara V. Howard, PhD; Cynthia A. Thomson, PhD, RD; Andrea Z. LaCroix, PhD; Jean Wactawski-Wende, PhD; Rebecca D. Jackson, MD; Marian Limacher, MD; Karen L. Margolis, MD, MPH; Sylvia Wassertheil-Smoller, PhD; Shirley A. Beresford, PhD; Jane A. Cauley, DrPH; Charles B. Eaton, MD, MS; Margery Gass, MD, NCMP; Judith Hsia, MD; Karen C. Johnson, MD, MPH; Charles Kooperberg, PhD; Lewis H. Kuller, MD, DrPH; Cora E. Lewis, MD, MSPH; Simin Liu, MD, ScD; Lisa W. Martin, MD; Judith K. Ockene, PhD; Mary Jo O’Sullivan, MD; Lynda H. Powell, PhD; Michael S. Simon, MD, MPH; Linda Van Horn, PhD, RD; Mara Z. Vitolins, DrPH, RD; Robert B. Wallace, MD, MSc
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JAMA. 2013; 310(13):1353-1368. doi: 10.1001/jama.2013.278040Manson and coauthors provide an update and overview of health outcomes during the intervention and poststopping phases of the Women’s Health Initiative (WHI) hormone therapy trials. In an accompanying Editorial, Nabel discusses how the WHI is a victory for women and their health.
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JAMA
Original Contribution
April 6, 2011
Andrea Z. LaCroix, PhD; Rowan T . Chlebowski , MD, PhD; JoAnn E. Manson, MD, DrPH; Aaron K. Aragaki, MS; Karen C. Johnson, MD, MPH; Lisa Martin, MD; Karen L. Margolis, MD, MPH; Marcia L. Stefanick, PhD; Robert Brzyski, MD, PhD; J. David Curb, MD, MPH; Barbara V. Howard, PhD; Cora E. Lewis, MD, MSPH; Jean Wactawski-Wende, PhD; for the WHI Investigators
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JAMA. 2011; 305(13):1305-1314. doi: 10.1001/jama.2011.382
JAMA
Letters
February 2, 2011
Rowan T . Chlebowski , MD, PhD; Marcia L. Stefanick, PhD; Garnet L. Anderson, PhD
JAMA. 2011; 305(5):466-467. doi: 10.1001/jama.2011.76
JAMA
Original Contribution
Clinician's Corner
October 20, 2010
Rowan T . Chlebowski , MD, PhD; Garnet L. Anderson, PhD; Margery Gass, MD; Dorothy S. Lane, MD; Aaron K. Aragaki, MS; Lewis H. Kuller, MD; JoAnn E. Manson, MD, DrPH; Marcia L. Stefanick, PhD; Judith Ockene, MD; Gloria E. Sarto, MD; Karen C. Johnson, MD, MPH; Jean Wactawski-Wende, PhD; Peter M. Ravdin, MD, PhD; Robert Schenken, MD; Susan L. Hendrix, DO; Aleksandar Rajkovic, MD, PhD; Thomas E. Rohan, PhD; Shagufta Yasmeen, MD; Ross L. Prentice, PhD; for the WHI Investigators
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JAMA. 2010; 304(15):1684-1692. doi: 10.1001/jama.2010.1500
JAMA Internal Medicine
Original Investigation
October 12, 2009
Carolyn J. Crandall, MD, MS; Aaron K. Aragaki, MS; Rowan T . Chlebowski , MD, PhD; Anne McTiernan, MD, PhD; Garnet Anderson, PhD; Susan L. Hendrix, DO; Barbara B. Cochrane, PhD, RN; Lewis H. Kuller, MD, DrPH; Jane A. Cauley, DrPH
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Arch Intern Med. 2009; 169(18):1684-1691. doi: 10.1001/archinternmed.2009.303
JAMA
Letters
June 18, 2008
Rowan T . Chlebowski , MD, PhD
JAMA. 2008; 299(23):2744-2745. doi: 10.1001/jama.299.23.2744-b
JAMA
Original Contribution
March 5, 2008
Gerardo Heiss, MD; Robert Wallace, MD; Garnet L. Anderson, PhD; Aaron Aragaki, MS; Shirley A. A. Beresford, PhD; Robert Brzyski, MD; Rowan T . Chlebowski , MD; Margery Gass, MD; Andrea LaCroix, PhD; JoAnn E. Manson, MD; Ross L. Prentice, PhD; Jacques Rossouw, MD; Marcia L. Stefanick, PhD; for the WHI Investigators
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JAMA. 2008; 299(9):1036-1045. doi: 10.1001/jama.299.9.1036
JAMA Internal Medicine
Original Investigation
February 25, 2008
Rowan T . Chlebowski , MD, PhD; Garnet Anderson, PhD; Mary Pettinger, MS; Dorothy Lane, MD, MPH; Robert D. Langer, MD, MPH; Mary Ann Gillian, MD, MPH; Brian W. Walsh, MD; Chu Chen, PhD; Anne McTiernan, MD, PhD; Women's Health Initiative Investigators
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Arch Intern Med. 2008; 168(4):370-377. doi: 10.1001/archinternmed.2007.123