This study evaluates changes in medical exemptions and geographic distribution of kindergarteners in California not up to date on vaccination after changes to state legislation.

This cohort study assesses within- and between-hospital variance in COVID-19 treatment and outcomes associated with race among hospitalized US veterans.

This case series examines the differences in COVID-19 vaccine mandates for schoolteachers vs childcare professionals from US states that have implemented them.

This cross-sectional study evaluates changes in homeschooling rates among kindergarten through grade 8 students before and after California’s Senate Bill No. 277 eliminated nonmedical exemptions to vaccination requirements in the state.

This survey study assesses whether child masking policies are associated with COVID-19–related childcare program closures.

This Viewpoint discusses the Omicron variant of SARS-CoV-2, including its likely origin, the importance of vaccination, the other tools available to combat a surge in COVID-19 cases, and the possibility of a “twindemic” with influenza.

This study assesses state-level legal interventions to promote or impede COVID-19 vaccine mandates in the US since the beginning of the pandemic.

This Viewpoint discusses the Delta variant of SARS-CoV-2, including its epidemiology, transmissibility, how uneven vaccination coverage in the US encouraged its spread, and the most effective public health responses to curb it.

This study uses national survey data to describe overall and regional trends in adherence to protective behaviors (mask wearing, physical distancing, staying at home, others) among US adults during the COVID-19 pandemic from April to November 2020.

This JAMA Insights Clinical Update discusses herd immunity in the context of the COVID-19 pandemic and explains the herd immunity threshold as a function of transmissibility (R₀), the role of an effective vaccine and vaccination program in sustaining herd immunity, and the risks of an infection-based herd immunity approach.

This cross-sectional study evaluates the prevalence and sociodemographic disparities in influenza vaccination among a nationally representative sample of individuals with atherosclerotic cardiovascular disease.

This JAMA Insights feature provides a narrative update of a 2016 systematic review documenting an association between vaccine refusal and measles epidemiology in the US, and reaffirms based on the new evidence that vaccine refusal remains a significant contributor to measles resurgence in the postelimination era.

This Viewpoint provides a summary update of coronavirus disease 2019 (COVID-19) in the US, discussing case-fatality rates, interpretation of polymerase chain reaction test results, duration of immunity, reinfection, and more.

This observational study uses yearly cross-sectional school-entry data to calculate changes in rates of kindergartners attending California schools who were not up to date on required vaccinations before and after legislative and administrative initiatives in 2014-2017 intended to increase vaccine uptake.

This Viewpoint reviews measles outbreaks in the United States since the year 2000 attributable to vaccine hesitancy, refusal, and exemption, and specifies the costs to individuals, society, and health systems as a result.

This Viewpoint discusses ways to guide productive vaccine discussions in the clinic.

This Special Communication examines childhood vaccine policy in the context of varying outcomes and values.

This Viewpoint discusses the benefits of establishing a global vaccine injury compensation system that is government and manufacturer supported to compensate individuals who experience vaccine injury.