JAMA Network Open
Original Investigation
Geriatrics
March 31, 2022
Sarinnapha M. Vasunilashorn, PhD; Tamara G. Fong, MD, PhD; Benjamin K. I. Helfand, MSc; Tammy T. Hshieh, MD, MPH; Edward R. Marcantonio, MD, SM; Eran D. Metzger, MD; Eva M. Schmitt, PhD; Patricia A. Tabloski, PhD; Thomas G. Travison, PhD; Yun Gou, MA; Richard N. Jones, ScD; Sharon K . Inouye , MD, MPH; BASIL Study Team
open access
JAMA Netw Open. 2022; 5(3):e226129. doi: 10.1001/jamanetworkopen.2022.6129
This cohort study examines the internal consistency, reliability, and validity for clinical outcomes of a measure of delirium severity that was developed using advanced psychometric approaches.
JAMA Network Open
Editorial
March 24, 2022
Ishani Ganguli, MD, MPH; Frederick P. Rivara, MD, MPH; Sharon K . Inouye , MD, MPH
open access
JAMA Netw Open. 2022; 5(3):e223940. doi: 10.1001/jamanetworkopen.2022.3940
JAMA Internal Medicine
Original Investigation
March 1, 2022
Alison M. Mudge, MBBS, PhD; Prue McRae, BPhty, MPhil; Merrilyn Banks, PhD; Irene Blackberry, PhD; Sally Barrimore, MNutrDiet; John Endacott, MBBS; Nicholas Graves, PhD; Theresa Green, RN, PhD; Gill Harvey, PhD; Ruth Hubbard, MBBS, MD; Sue Kurrle, MD, PhD; Wen Kwang Lim, MBBS, MD; Karen Lee-Steere, BSci(OccThy); Phil Masel, MBBS; Shaun Pandy, MBBS; Adrienne Young, PhD; Adrian Barnett, PhD; Sharon K . Inouye , MD, MPH
JAMA Intern Med. 2022; 182(3):274-282. doi: 10.1001/jamainternmed.2021.7556
This cluster randomized clinical trial evaluates a hospital ward–based improvement program (“Eat Walk Engage”) to more consistently deliver age-friendly principles to older individuals in acute inpatient wards.
JAMA Network Open
Original Investigation
Anesthesiology
December 13, 2021
Jordan Oberhaus, BA; Wei Wang, PhD; Angela M. Mickle, MS; Jennifer Becker, MD; Catherine Tedeschi, MD; Hannah R. Maybrier, BS; Ravi T. Upadhyayula, MD; Maxwell R. Muench, DO; Nan Lin, PhD; Eva M. Schmitt, PhD; Sharon K . Inouye , MD, MPH; Michael S. Avidan, MBBCh
open access
JAMA Netw Open. 2021; 4(12):e2137267. doi: 10.1001/jamanetworkopen.2021.37267
This cohort study evaluates the performance of the 3-Minute Diagnostic Confusion Assessment Method (3D-CAM) for detecting postoperative delirium in older patients.
JAMA Network Open
Editorial
September 8, 2021
Elizabeth A. Jacobs, MD, MAPP; Ishani Ganguli, MD, MPH; Sharon K . Inouye , MD, MPH
open access
JAMA Netw Open. 2021; 4(9):e2123364. doi: 10.1001/jamanetworkopen.2021.23364
JAMA Network Open
Editorial
June 16, 2021
Sharon K . Inouye , MD, MPH; Ishani Ganguli, MD, MPH; Elizabeth A. Jacobs, MD, MPP
open access
JAMA Netw Open. 2021; 4(6):e2117621. doi: 10.1001/jamanetworkopen.2021.17621
JAMA Network Open
Editorial
June 11, 2021
Frederick P. Rivara, MD, MPH; Steven M. Bradley, MD, MPH; Daniel V. Catenacci, MD; Angel N. Desai, MD; Ishani Ganguli, MD, MPH; Sebastien J. P. A. Haneuse, PhD; Sharon K . Inouye , MD, MPH; Elizabeth A. Jacobs, MD, MAPP; Kristin Kan, MD, MPH, MSc; Howard S. Kim, MD, MS; Arden M. Morris, MD, MPH; Olugbenga Ogedegbe, MD, MS, MPH; Eli N. Perencevich, MD, MS; Roy H. Perlis, MD, MSc; Elizabeth Powell, MD, MPH; Gordon D. Rubenfeld, MD, MSc; Lawrence N. Shulman, MD; N. Seth Trueger, MD, MPH; Stephan D. Fihn, MD, MPH
open access
JAMA Netw Open. 2021; 4(6):e2120269. doi: 10.1001/jamanetworkopen.2021.20269
JAMA
JAMA Insights
May 4, 2021
Sharon K . Inouye , MD, MPH
free access
is active quiz
JAMA. 2021; 325(17):1779-1780. doi: 10.1001/jama.2021.2211
This JAMA Insights Clinical Update discusses the underrecognition of delirium in older adults with COVID-19 and provides delirium prevention strategies for hospitalized patients, such as providing remote visits with family members and therapeutic activity kits to the bedside.
JAMA Surgery
Original Investigation
May 1, 2021
Ray Yun Gou, MA; Tammy T. Hshieh, MD, MPH; Edward R. Marcantonio, MD, SM; Zara Cooper, MD, MSc; Richard N. Jones, ScD; Thomas G. Travison, PhD; Tamara G. Fong, MD, PhD; Ayesha Abdeen, MD; Jeffrey Lange, MD; Brandon Earp, MD; Eva M. Schmitt, PhD; Douglas L. Leslie, PhD; Sharon K . Inouye , MD, MPH; SAGES Study Group
free access
JAMA Surg. 2021; 156(5):430-442. doi: 10.1001/jamasurg.2020.7260
This cohort study uses data from the Successful Aging after Elective Surgery (SAGES) study, an ongoing cohort study of older adults undergoing major elective surgery at 2 acute care hospitals, to assess the Medicare costs associated with delirium in older adults 1 year after major elective surgery.
JAMA Network Open
Original Investigation
Emergency Medicine
November 19, 2020
Maura Kennedy, MD, MPH; Benjamin K. I. Helfand, MSc; Ray Yun Gou, MA; Sarah L. Gartaganis, MSW, MPH; Margaret Webb, BA; J. Michelle Moccia, DNP, ANP-BC, GS-C; Stacey N. Bruursema, LMSW-C; Belinda Dokic, MHA; Brigid McCulloch, DO; Hope Ring, MD; Justin D. Margolin, BS; Ellen Zhang, BA; Robert Anderson, MD; Rhonda L. Babine, MS, APRN, ACNS-BC; Tammy Hshieh, MD, MPH; Ambrose H. Wong, MD, MSEd; R. Andrew Taylor, MD, MHS; Kathleen Davenport, MD; Brittni Teresi, BA; Tamara G. Fong, MD, PhD; Sharon K . Inouye , MD, MPH
open access
is active quiz
JAMA Netw Open. 2020; 3(11):e2029540. doi: 10.1001/jamanetworkopen.2020.29540
This cohort study examines how frequently older adults with coronavirus disease 2019 (COVID-19) present to the emergency department with delirium and their associated hospital outcomes.
JAMA Internal Medicine
Research Letter
November 1, 2020
Benjamin K. I. Helfand, MSc; Margaret Webb, BA; Sarah L. Gartaganis, MSW, MPH; Lily Fuller, BA; Churl-Su Kwon, MD, MPH; Sharon K . Inouye , MD, MPH
free access
has multimedia
JAMA Intern Med. 2020; 180(11):1546-1549. doi: 10.1001/jamainternmed.2020.5084
This cross-sectional study evaluates the risk of exclusion for older adults in randomized clinical trials for treatment and vaccine interventions in coronavirus disease 2019.
JAMA Internal Medicine
Original Investigation
January 1, 2020
Yan-Yan Wang, PhD; Ji-Rong Yue, MD; Dong-Mei Xie, BSN; Patricia Carter, PhD; Quan-Lei Li, MPH, MSN, PhDc; Sarah L. Gartaganis, MSW; Jie Chen, MD, PhD; Sharon K . Inouye , MD, MPH
free access
JAMA Intern Med. 2020; 180(1):17-25. doi: 10.1001/jamainternmed.2019.4446
This randomized clinical trial evaluates the effectiveness of a delirium prevention intervention incorporating family and caregiver participation for reducing postoperative delirium and functional decline in older patients in China.
JAMA
Original Investigation
February 5, 2019
Troy S. Wildes, MD; Angela M. Mickle, MS; Arbi Ben Abdallah, PhD; Hannah R. Maybrier, BS; Jordan Oberhaus, BS; Thaddeus P. Budelier, MD, MSF; Alex Kronzer, BA; Sherry L. McKinnon, BS; Daniel Park, BS; Brian A. Torres, DNP; Thomas J. Graetz, MD; Daniel A. Emmert, MD, PhD; Ben J. Palanca, MD, PhD; Shreya Goswami, MBBS, DNB; Katherine Jordan, BS; Nan Lin, PhD; Bradley A. Fritz, MD; Tracey W. Stevens, MD; Eric Jacobsohn, MBChB, MPHE, FRCPC; Eva M. Schmitt, PhD; Sharon K . Inouye , MD, MPH; Susan Stark, PhD; Eric J. Lenze, MD; Michael S. Avidan, MBBCh; for the ENGAGES Research Group
free access
JAMA. 2019; 321(5):473-483. doi: 10.1001/jama.2018.22005
This pragmatic randomized trial compares the effects of EEG-guided anesthetic administration vs usual anesthetic care on incident postoperative delirium among older adults undergoing major surgery.
JAMA Internal Medicine
Review
February 1, 2019
Richard N. Jones, ScD; Sevdenur Cizginer, MD; Laura Pavlech, DVM, MSLS; Asha Albuquerque, BA; Lori A. Daiello, PharmD, ScM; Kumar Dharmarajan, MD, MBA; Lauren J. Gleason, MD, MPH; Benjamin Helfand, MSc; Lauren Massimo, PHD, CRNP; Esther Oh, MD, PhD; Olivia I. Okereke, MD, MS; Patricia Tabloski, GNP-BC, PhD; Laura A. Rabin, MD; Jirong Yue, MD; Edward R. Marcantonio, MD, SM; Tamara G. Fong, MD, PhD; Tammy T. Hshieh, MD, MPH; Eran D. Metzger, MD; Kristen Erickson, MPH; Eva M. Schmitt, PhD; Sharon K . Inouye , MD, MPH; for the Better Assessment of Illness (BASIL) Study Group
JAMA Intern Med. 2019; 179(2):231-239. doi: 10.1001/jamainternmed.2018.6975
This systematic review summarizes the criteria and methodology used to identify high-quality delirium severity instruments.
JAMA Internal Medicine
Invited Commentary
September 1, 2018
Matthew E. Growdon, MD, MPH; Sharon K . Inouye , MD, MPH
JAMA Intern Med. 2018; 178(9):1208-1209. doi: 10.1001/jamainternmed.2018.2679
JAMA
Review
September 26, 2017
Esther S. Oh, MD, PhD; Tamara G. Fong, MD, PhD; Tammy T. Hshieh, MD, MPH; Sharon K . Inouye , MD, MPH
JAMA. 2017; 318(12):1161-1174. doi: 10.1001/jama.2017.12067
This narrative review summarizes recent advances in the prevention, diagnosis, and treatment of delirium and highlights critical areas for future research.
JAMA Surgery
Original Investigation
September 1, 2017
Cheryl Chia-Hui Chen, RN, DNSc; Hsiu-Ching Li, RN, MSN; Jin-Tung Liang, MD, PhD; I-Rue Lai, MD, PhD; Jerry Dwi Trijoyo Purnomo, MS; Yi-Ting Yang, RN, MSN; Been-Ren Lin, MD, PhD; John Huang, MD; Ching-Yao Yang, MD, PhD; Yu-Wen Tien, MD, PhD; Chiung-Nien Chen, MD, PhD; Ming-Tsan Lin, MD, PhD; Guan-Hua Huang, PhD; Sharon K . Inouye , MD, MPH
free access
JAMA Surg. 2017; 152(9):827-834. doi: 10.1001/jamasurg.2017.1083
This cluster randomized clinical trial examines whether a modified Hospital Elder Life Program reduces incident delirium and length of stay in older patients undergoing abdominal surgery.
JAMA Internal Medicine
Viewpoint
Health Care Policy and Law
June 1, 2017
Matthew E. Growdon, MD, MPH; Ronald I. Shorr, MD, MS; Sharon K . Inouye , MD, MPH
JAMA Intern Med. 2017; 177(6):759-760. doi: 10.1001/jamainternmed.2017.0840
This Viewpoint explains the Hospital Elder Life Program (HELP), which enhances mobility for elderly patients while decreasing the risk of falls in the hospital setting, and how implementing programs like HELP can have several potentially beneficial effects.
JAMA Psychiatry
Editorial
March 1, 2017
Tamara G. Fong, MD, PhD; Sharon K . Inouye , MD, MPH; Richard N. Jones, ScD
JAMA Psychiatry. 2017; 74(3):212-213. doi: 10.1001/jamapsychiatry.2016.3812
JAMA Surgery
Original Investigation
December 1, 2015
Lauren J. Gleason, MD; Eva M. Schmitt, PhD; Cyrus M. Kosar, MA; Patricia Tabloski, PhD; Jane S. Saczynski, PhD; Thomas Robinson, MD; Zara Cooper, MD; Selwyn O. Rogers Jr, MD, MPH; Richard N. Jones, ScD; Edward R. Marcantonio, MD, SM; Sharon K . Inouye , MD, MPH
free access
JAMA Surg. 2015; 150(12):1134-1140. doi: 10.1001/jamasurg.2015.2606
This prospective cohort study found that postoperative complications and delirium are separately associated with adverse events and demonstrate a combined effect.