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  • Seven Questions for Personalized Medicine

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    JAMA. 2015; 314(10):999-1000. doi: 10.1001/jama.2015.7725

    This Viewpoint discusses the promise of personalized or precision medicine compared with its achievements to date.

  • Seven Legal Barriers to End-of-Life Care: Myths, Realities, and Grains of Truth

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    JAMA. 2000; 284(19):2495-2501. doi: 10.1001/jama.284.19.2495
  • Users' Guides to the Medical Literature: XVI. How to Use a Treatment Recommendation

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    JAMA. 1999; 281(19):1836-1843. doi: 10.1001/jama.281.19.1836
  • Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons: US Preventive Services Task Force Recommendation Statement

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    JAMA. 2021; 325(3):265-279. doi: 10.1001/jama.2020.25019

    This 2021 US Preventive Services Task Force Recommendation Statement recommends that clinicians ask all adults about tobacco use, advise them to stop using tobacco, and provide behavioral interventions and pharmacotherapy for cessation (A recommendation) and concludes that evidence is insufficient to assess the benefits and harms of tobacco cessation pharmacotherapy in pregnant persons and e- cigarettes for tobacco cessation in any adult (I statement).

  • Association of Matched Sibling Donor Hematopoietic Stem Cell Transplantation With Transcranial Doppler Velocities in Children With Sickle Cell Anemia

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    JAMA. 2019; 321(3):266-276. doi: 10.1001/jama.2018.20059

    This nonrandomized controlled intervention study compared the effect of matched sibling donor hematopoietic stem cell transplantation (HSCT) vs standard care comprising transfusions and hydroxyurea on transcranial Doppler velocities, a measure of cerebral vasculopathy, at 1 year in children with sickle cell anemia requiring chronic transfusion.

  • Prevalence of Continuous Pulse Oximetry Monitoring in Hospitalized Children With Bronchiolitis Not Requiring Supplemental Oxygen

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    JAMA. 2020; 323(15):1467-1477. doi: 10.1001/jama.2020.2998

    This study characterizes use of continuous pulse oximetry monitoring in hospitalized children with bronchiolitis who do not require supplemental oxygen in Canadian and US hospitals.

  • Association Between Long-Lasting Intravitreous Fluocinolone Acetonide Implant vs Systemic Anti-inflammatory Therapy and Visual Acuity at 7 Years Among Patients With Intermediate, Posterior, or Panuveitis

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    JAMA. 2017; 317(19):1993-2005. doi: 10.1001/jama.2017.5103

    This study reports 7-year outcomes data for patients with uveitis randomized in the Multicenter Uveitis Steroid Treatment trial to receive an intravitreous fluocinolone acetonide implant vs prednisone or other immunosuppressant therapy.

  • Clinical Risk Score for Persistent Postconcussion Symptoms Among Children With Acute Concussion in the ED

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    JAMA. 2016; 315(10):1014-1025. doi: 10.1001/jama.2016.1203

    This multicenter cohort study describes a novel clinical risk score developed among children presenting to the emergency department with concussion and head injury within the previous 48 hours to stratify risk of persistent postconcussion symptoms at 28 days.

  • Use of Board Certification and Recertification of Pediatricians in Health Plan Credentialing Policies

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    JAMA. 2006; 295(8):913-918. doi: 10.1001/jama.295.8.913
  • Effect of Communication Skills Training for Residents and Nurse Practitioners on Quality of Communication With Patients With Serious Illness: A Randomized Trial

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    JAMA. 2013; 310(21):2271-2281. doi: 10.1001/jama.2013.282081

    In a randomized trial evaluating the effects of a communication skills intervention for internal medicine and nurse practitioner trainees, Curtis and coauthors measured patient- and family-reported outcomes including quality of communication. In an Editorial, Verghese and Chi discuss the findings in the context of improving communication with patients.

  • Perceptions of Appropriateness of Care Among European and Israeli Intensive Care Unit Nurses and Physicians

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    JAMA. 2011; 306(24):2694-2703. doi: 10.1001/jama.2011.1888
  • Cardiac Outcomes After Screening for Asymptomatic Coronary Artery Disease in Patients With Type 2 Diabetes: The DIAD Study: A Randomized Controlled Trial

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    JAMA. 2009; 301(15):1547-1555. doi: 10.1001/jama.2009.476
  • Screening for Elevated Blood Lead Levels in Children and Pregnant Women: US Preventive Services Task Force Recommendation Statement

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    JAMA. 2019; 321(15):1502-1509. doi: 10.1001/jama.2019.3326

    This 2019 Recommendation Statement from the US Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for elevated blood lead levels in asymptomatic children (I statement) and asymptomatic pregnant persons (I statement).

  • Clinical Interpretation and Implications of Whole-Genome Sequencing

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    JAMA. 2014; 311(10):1035-1045. doi: 10.1001/jama.2014.1717

    Dewey and colleagues found that depending on the sequencing platform used, there was incomplete coverage of inherited disease genes, low reproducibility of potentially clinically significant genetic variation, and uncertainty about clinically reportable findings.

  • Changing Epidemiology of Invasive Pneumococcal Disease Among Older Adults in the Era of Pediatric Pneumococcal Conjugate Vaccine

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    JAMA. 2005; 294(16):2043-2051. doi: 10.1001/jama.294.16.2043
  • A Health Workbook for College Freshmen: An Orientation Course in Personal, Home, and Community Hygiene

    Abstract Full Text
    JAMA. 1934; 102(20):1706-1706. doi: 10.1001/jama.1934.02750200056032
  • Delirium in Older Persons: Advances in Diagnosis and Treatment

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    JAMA. 2017; 318(12):1161-1174. doi: 10.1001/jama.2017.12067

    This narrative review summarizes recent advances in the prevention, diagnosis, and treatment of delirium and highlights critical areas for future research.

  • Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement

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    JAMA. 2018; 320(18):1899-1909. doi: 10.1001/jama.2018.16789

    This 2018 Recommendation Statement from the US Preventive Services Task Force recommends screening for unhealthy alcohol use in primary care settings in adults, including pregnant women, and providing brief behavioral counseling to reduce unhealthy alcohol use (B recommendation) and concludes that evidence is insufficient to assess balance of benefits and harms of screening and counseling for alcohol use in primary care settings in adolescents (I statement).

  • Fluoxetine, Cognitive-Behavioral Therapy, and Their Combination for Adolescents With Depression: Treatment for Adolescents With Depression Study (TADS) Randomized Controlled Trial

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    JAMA. 2004; 292(7):807-820. doi: 10.1001/jama.292.7.807
  • Screening for Elevated Blood Lead Levels in Childhood and Pregnancy: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

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    JAMA. 2019; 321(15):1510-1526. doi: 10.1001/jama.2019.1004

    This systematic review to support the 2019 US Preventive Services Task Force Recommendation Statement on screening for elevated blood lead levels in childhood and pregnancy summarizes published evidence on the benefits and harms of screening and intervention for elevated blood lead levels in pregnant women and children 5 years and younger in the primary care setting.