JAMA
US Preventive Services Task Force
Evidence Report
April 13, 2021
Leila C. Kahwati, MD, MPH; Erin LeBlanc, MD, MPH; Rachel Palmieri Weber, PhD; Kayla Giger, BS; Rachel Clark, BA; Kara Suvada, BS; Amy Guisinger, BS; Meera Viswanathan, PhD
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JAMA. 2021; 325(14):1443-1463. doi: 10.1001/jama.2020.26498This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on screening for vitamin D deficiency summarizes published evidence on the benefits and harms of screening and interventions for vitamin D deficiency in asymptomatic, community-dwelling adults.
JAMA
US Preventive Services Task Force
Recommendation Statement
April 13, 2021
US Preventive Services Task Force
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JAMA. 2021; 325(14):1436-1442. doi: 10.1001/jama.2021.3069This 2021 US Preventive Services Task Force Recommendation Statement concludes that current evidence is insufficient to assess the balance of benefits and harms of screening for vitamin D deficiency in asymptomatic adults (I statement).
JAMA
Medical News & Perspectives
Quick Uptakes
January 26, 2021
Rita Rubin, MA
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JAMA. 2021; 325(4):329-330. doi: 10.1001/jama.2020.24127This Medical News Quick Uptake examines the debate about a link between vitamin D and COVID-19 risk.
JAMA
Original Investigation
November 10, 2020
Heike A. Bischoff-Ferrari, MD, DrPH; Bruno Vellas, MD, PhD; René Rizzoli, MD; Reto W. Kressig, MD; José A. P. da Silva, MD, PhD; Michael Blauth, MD; David T. Felson, MD, MPH; Eugene V. McCloskey, MD; Bernhard Watzl, PhD; Lorenz C. Hofbauer, MD; Dieter Felsenberg, MD, PhD; Walter C. Willett, MD; Bess Dawson-Hughes, MD; JoAnn E. Manson, MD, DrPH; Uwe Siebert, MD, MPH; Robert Theiler, MD; Hannes B. Staehelin, MD; Caroline de Godoi Rezende Costa Molino, PhD; Patricia O. Chocano-Bedoya, MD, PhD; Lauren A. Abderhalden, PhD; Andreas Egli, MD; John A. Kanis, MD; Endel J. Orav, PhD; DO-HEALTH Research Group
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JAMA. 2020; 324(18):1855-1868. doi: 10.1001/jama.2020.16909This randomized trial compares the effects of vitamin D, omega-3s, and a strength-training exercise program alone or in combination vs no supplementation and control exercise on changes in blood pressure, physical and cognitive function, nonvertebral fractures, and infections over 3 years among older adults.
JAMA
Clinical Trials Update
October 27, 2020
Anita Slomski
JAMA. 2020; 324(16):1599-1599. doi: 10.1001/jama.2020.18695
JAMA
Original Investigation
August 25, 2020
Erick Forno, MD, MPH; Leonard B. Bacharier, MD; Wanda Phipatanakul, MD, MS; Theresa W. Guilbert, MD, MS; Michael D . Cabana, MD, MPH; Kristie Ross, MD, MS; Ronina Covar, MD; James E. Gern, MD; Franziska J. Rosser, MD, MPH; Joshua Blatter, MD, MPH; Sandy Durrani, MD; Yueh-Ying Han, PhD; Stephen R. Wisniewski, PhD; Juan C. Celedón, MD, DrPH
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JAMA. 2020; 324(8):752-760. doi: 10.1001/jama.2020.12384This randomized trial compares the effects of vitamin D3 vs placebo on time to severe exacerbation in children with asthma and low vitamin D levels.
JAMA
Medical News & Perspectives
December 3, 2019
Jennifer Abbasi
JAMA. 2019; 322(21):2061-2064. doi: 10.1001/jama.2019.18830This Medical News article discusses the top-viewed Original Investigations and Special Communications published across the JAMA Network over 12 months.
JAMA
Editorial
November 19, 2019
Anika Lucas, MD; Myles Wolf, MD, MMSc
JAMA. 2019; 322(19):1866-1868. doi: 10.1001/jama.2019.17302
JAMA
Original Investigation
November 19, 2019
Ian H. de Boer, MD, MS; Leila R. Zelnick, PhD; John Ruzinski, BS; Georgina Friedenberg, MPH; Julie Duszlak, BS; Vadim Y. Bubes, PhD; Andrew N. Hoofnagle, MD, PhD; Ravi Thadhani, MD, MPH; Robert J. Glynn, PhD, ScD; Julie E. Buring, ScD; Howard D . Sesso, ScD, MPH; JoAnn E. Manson, MD, DrPH
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JAMA. 2019; 322(19):1899-1909. doi: 10.1001/jama.2019.17380This 2 × 2 factorial trial compares the effects of vitamin D3 vs placebo and omega-3 fatty acids vs placebo on change in glomerular filtration rate estimated from serum creatinine and cystatin C (eGFR) over 5 years in adults with type 2 diabetes.
JAMA
Clinical Trials Update
August 27, 2019
Anita Slomski, MA
JAMA. 2019; 322(8):717-717. doi: 10.1001/jama.2019.11564
JAMA
Original Investigation
August 27, 2019
Lauren A. Burt, PhD; Emma O. Billington, MD, FRCPC; Marianne S. Rose, PhD; Duncan A. Raymond, MS; David A. Hanley, MD, FRCPC; Steven K. Boyd, PhD
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JAMA. 2019; 322(8):736-745. doi: 10.1001/jama.2019.11889This randomized trial compares the effects of 400 vs 4000 vs 10 000 IU of vitamin D on total volumetric bone mineral density and bone strength of the radius and tibia.
JAMA
Editorial
April 9, 2019
Elizabeth L. Barry, PhD; Michael N. Passarelli, PhD; John A. Baron, MD, MS, MSc
JAMA. 2019; 321(14):1354-1355. doi: 10.1001/jama.2019.2589
JAMA
Original Investigation
April 9, 2019
Mitsuyoshi Urashima, MD; Hironori Ohdaira, MD; Taisuke Akutsu, MD; Shinya Okada, MD; Masashi Yoshida, MD; Masaki Kitajima, MD; Yutaka Suzuki, MD
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JAMA. 2019; 321(14):1361-1369. doi: 10.1001/jama.2019.2210This randomized clinical trial compares the effects of vitamin D supplementation vs placebo on 5-year relapse-free survival after surgical resection of stage I-III esophageal, gastric, small bowel, and colorectal cancers.
JAMA
Original Investigation
March 16, 2021
Christine M. Albert, MD, MPH; Nancy R. Cook, ScD; Julie Pester, BA; M. Vinayaga Moorthy, PhD; Claire Ridge, MPH; Jacqueline S. Danik, MD, DrPH; Baris Gencer, MD; Hasan K. Siddiqi, MD, MSCR; Chee Ng, MD; Heike Gibson, PhD; Samia Mora, MD, MHS; Julie E. Buring, ScD; JoAnn E. Manson, MD, DrPH
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JAMA. 2021; 325(11):1061-1073. doi: 10.1001/jama.2021.1489This 2 × 2 factorial trial compares the effects of omega-3 fatty acids (460 mg/d of EPA and 380 mg/d of DHA) vs placebo, vitamin D₃ vs placebo, both, or neither on risk of incident atrial fibrillation (AF) among adults aged 50 years or older over a median of more than 5 years of treatment.
JAMA
Research Letter
March 12, 2019
Nicklas Brustad, MD; Anders U. Eliasen, MSc; Jakob Stokholm, MD, PhD; Klaus Bønnelykke, MD, PhD; Hans Bisgaard, MD, DMSc; Bo L. Chawes, MD, PhD, DMSc
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JAMA. 2019; 321(10):1003-1005. doi: 10.1001/jama.2019.0052This long-term follow-up of a randomized trial reporting no apparent effect of high-dose vs standard-dose prenatal vitamin D supplementation on wheezing in children at the age of 3 years extends the findings an additional 3 years and describes asthma risk at the age of 6 years.
JAMA
Original Investigation
May 22, 2018
Anna Maria Hibbs, MD, MSCE; Kristie Ross, MD, MS; Leigh Ann Kerns, MD; Carol Wagner, MD; Mamta Fuloria, MD; Sharon Groh-Wargo, PhD, RD; Teresa Zimmerman, MD; Nori Minich; Curtis Tatsuoka, PhD
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JAMA. 2018; 319(20):2086-2094. doi: 10.1001/jama.2018.5729This randomized clinical trial compares the effects of 2 vitamin D dosing strategies on recurrent wheezing in black infants at 12months of age who were born preterm.
JAMA
Editorial
May 22, 2018
Frank R. Greer, MD
JAMA. 2018; 319(20):2081-2082. doi: 10.1001/jama.2018.5726